Dr Gary Fettke - Nutrition and cancer – Time to rethink



Nutrition and cancer â?? Time to rethink
Dr Gary Fettke

In 1931 Otto Warburg received the Nobel Prize for showing that cancer cells have an absolute requirement to use glucose for their energy requirements since they lack proper mitochondrial function for oxidizing fats. This suggests that nutritional factors in particular low or high carbohydrate diets might influence cancer outcomes differently. In my presentation I will present the evidence showing that certain cancers may be carbohydrate-dependant and may be positively influenced by the ingestion of low carbohydrate ketogenic diets which reduce the provision of glucose to the tumour cells.

Cancer as a metabolic disease
Seyfried T N et al. Carcinogenesis 2013;carcin.bgt480
http://carcin.oxfordjournals.org/cont...

Cancer Statistics, Trends, and Multiple Primary Cancer Analyses from the Surveillance, Epidemiology, and End Results (SEER) Program
http://theoncologist.alphamedpress.or...
Fouche FP: Freedom of Negro Races from Cancer, Br Med J. 1923 Jun
http://www.ncbi.nlm.nih.gov/pmc/artic...
Renehan G et al. Obesity and Cancer: Physiological and biological mechanisms. Archives of Physiology and Biochemistry, 2 2008; 114(1): 71-83
http://informahealthcare.com/doi/abs/...
Giovannucci et al. Diabetes and cancer: a consensus report. CA Cancer J Clin 2010;60:207-221
http://onlinelibrary.wiley.com/doi/10...
Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Vander Heiden et al. Science 2009; science. 1160809
http://www.ncbi.nlm.nih.gov/pubmed/19...
Cancer cells metabolically â??fertilizeâ? the tumor microenvironment with hydrogen peroxide, driving the Warburg effect
Lisanti et al. Cell Cycle, 2011; 10(15); 2504-2520
http://www.ncbi.nlm.nih.gov/pmc/artic...
Chan et al, Are we ready to recommend aspirin for the prevention of cancer? Lancet. Apr 28,2012; 379(9826): 1569-1571
http://www.thelancet.com/journals/lan...
Decensi et al, Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis. Cancer Prev Res, 2010 Nov;3(11):1451-61
http://cancerpreventionresearch.aacrj...
Lee et al, Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese. BMC Cancer. 2011;11:20
http://www.biomedcentral.com/1471-240...
Lv M, Zhu X, Wang H, Wang F, Guan W (2014) Roles of Caloric Restriction, Ketogenic Diet and Intermittent Fasting during Initiation, Progression and Metastasis of Cancer in Animal Models: A Systematic Review and Meta-Analysis. PLoS ONE 9(12): e115147. doi:10.1371/journal.pone.0115147
http://journals.plos.org/plosone/arti...
Schmidt et al. Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: a pilot trial. Nutrition & Metabolism 2011, 8:54
http://www.nutritionandmetabolism.com...
Fine et al. Nutrition, Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients. 28 (2012) 1028-1035
http://www.ncbi.nlm.nih.gov/pubmed/22...
Rieger et al. ERGO: a pilot study of ketogenic diet in recurrent glioblastoma. Int Journ Oncology 44: 1843-1852, 2014
http://www.ncbi.nlm.nih.gov/pmc/artic...
Champ, Volek et al. 2014. Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme. Jour Neurooncology DOI 10.1007/s11060-014-1362-0
http://www.ncbi.nlm.nih.gov/pubmed/24...
Human Clinical Trials
https://clinicaltrials.gov/ct2/result...
Raffaghello et al. Starvation-dependent differential stress resistance protects normal but not cancer cells against high dose chemotherapy. PNAS. 2008
http://www.pnas.org/content/105/24/82...
Klement and Champ. 2014 Calories, carbohydrates, and cancer therapy with radiation: exploiting the five Râ??s through dietary manipulation. Cancer Metastasis Rev. 2014; 33(1): 217â??229
http://www.ncbi.nlm.nih.gov/pubmed/24...
Novotny et al. A pessimistic explanatory style is prognostic for poor lung cancer survival. Jour Thoracic Oncology 2010 5(3):326-32
http://www.ncbi.nlm.nih.gov/pubmed/20...
Popkin et al. 2010,. Does hunger and satiety drive eating anymore? Increasing eating occasions and decreasing time between eating occasions in the United States Am J Clin Nutrition, 91: 1342-1347
http://www.ncbi.nlm.nih.gov/pubmed/20...
No Fructose
http://www.nofructose.com/

Video Length: 46:33
Uploaded By: Karen Thomson
View Count: 34,824


Like us on Facebook:
Follow us on Twitter:


End Boring Workouts! Shop Now at Aviron!
End Boring Workouts! Shop Now at Aviron!
Free Shipping on 69+ Free Shipping on any orders over $69.
Shop Diet Direct and get free shipping now!


Other videos by Karen Thomson
Dr Michael Eades - 30 years of flawed nutritional science
Dr Michael Eades - 30 years of flawed nutritional science
30 years of flawed nutritional science. What will it take for change to be accepted? Dr Michael Eades From my experience as an author, clinician and long-term ...
Video Length: 55:43
Uploaded By: Karen Thomson
View Count: 100,742

Featured Products
BariWise Pancake Mix, Golden Delicious (7ct)
BariWise Pancake Mix, Golden Delicious (7ct)

High Protein - 15 grams Per ServingLow Calorie - Only 90 caloriesLow Carbohydrate - 5g Net Carbs*Low Fat - 1 gram Per ServingSaturated Fat FreeTrans Fat FreeContains Less Than 1 gram of Sugar Per ...

Our Price: 14.95

Rating: 4 out of 5 stars (4 out of 5)


ProtiDiet Soup, Beef Vegetable (7ct)
ProtiDiet Soup, Beef Vegetable (7ct)

High Protein - 15 Grams per ServingLow Carb - 5g Net Carbs*Low Calorie - 80 Calories per ServingFat FreeLow Cholesterol - Just 5 mcg per ServingProvides 15% DV of CalciumEasy to PrepareComes in ...

Our Price: 13.95

Rating: 4 out of 5 stars (4 out of 5)


Bariatric Advantage Chewable Iron 60mg with Vitamin C, Lemon & Lime (270ct)
Bariatric Advantage Chewable Iron 60mg with Vitamin C, Lemon & Lime (270ct)

Contains Vitamin C and FOS For Easier AbsorptionPleasing Lemon Lime Flavor ...

Our Price: 86.25

Rating: 5 out of 5 stars (5 out of 5)


3-DAY BELLY FAT + SLIM WAIST HOME WORKOUT
3-DAY BELLY FAT + SLIM WAIST HOME WORKOUT
An effective way to lose belly fat and achieve a slimmer waist is to adopt simple healthy habits, such as exercising regularly and maintaining a balanced diet.
Video Length: 34:43
Uploaded By: Roberta's Gym
View Count: 49,290

We Dieted Like Chris Pratt For 30 Days
We Dieted Like Chris Pratt For 30 Days
Three men take on the challenge of working with nutritionist Kevin Libby (PH2 Nutrition) to go from Andy Dwyer to Star-Lord in one month. Credits: ...
Video Length: 09:54
Uploaded By: BuzzFeedBlue
View Count: 10,740,895

25 Minute Beginner/intermediate Step Workout Part I
25 Minute Beginner/intermediate Step Workout Part I
Quickie 25 Minute Basic Step Workout Grab your bench and get ready to work it, work it. We got some step sisters together for a step social and this happened.
Video Length: 25:38
Uploaded By: Step Fit with Bronwyn
View Count: 1,438,978